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    DILAPAN-S® is an osmotic cervical dilator made of patented AQUACRYL hydrogel. The rigid hygroscopic gel rod increases its volume by absorbing fluids and gradually dilating the cervix.

    After 4 hours, the 3 mm rod will have expanded to 8.3 mm and the 4 mm rod up to 10 mm. Simultaneously, Dilapan–S® initiates endogenous prostaglandin release causing collagen degradation which softens the cervix.

    Of all the available cervical osmotic dilators, Dilapan-S® achieves the greatest cervical dilation in the shortest timeframe and is well accepted by the patient.

    Dilapan–S® is sterilized by irradiation. It is manufactured in an ISO 9001 Certified facility, fully CE Marked and approved by FDA for sale in the United States.

    The Main Advantages of Using DILAPAN-S® Include:

    • DILAPAN-S® stimulates the release of endogenous prostaglandins, which degrade collagen fibers and soften the cervix.
    • Gradual, predictable and gentle dilation of Dilapan–S® is very well received by patients.
    • No undesirable pharmacological effects.
    • Patient comfort is manageable on-site and at home.

    Why Choose Dilapan-S® over Laminaria?

    • Dilapan-S® expands radially more rapidly, consistently, and to a greater degree than laminaria tents. Therefore, fewer Dilapan–S® can be inserted for shorter periods of time..
    • Dilapan–S® is uniform in shape and manufactured to specification. Thus improving predictability of the procedure.
    • Less risk of infection...Dilapan–S® is made of a synthetic AQUACRYL hydrogel...Laminaria is manufactured from dried seaweed stems.

    Research White Papers

    Dilapan–S® Introduction

    Dilapan-S®
    Introduction

    Dilapan-S®
    Comparison With Lams

    Dilapan-S®
    Labor Preinduction

    Size Availability:

    Dilapan–S<sup>®</sup> Size Chart

    Product Images (Before & After)

  • Cervical preparation prior to the termination of pregnancy

    Dilapan S Comparison with Lams
    (click video below for details)

    Unique combination of efficacy, safety and time-efficiency in cervical preparation

    Thanks to the patented hydrogel AQUACRYL®, DILAPAN-S® ensures atraumatic and time-predictable dilation of the cervix. For instrumentations, that require dilation under 6mm, the time of insertion of 1 piece dilator is shorter than 2 hours.

    Proven efficacy and safety prior to the termination of pregnancy

    "After 14 weeks of gestation, osmotic dilators provide superior dilatation to medical methods (grade B)" 
    Royal Colleqe of Obstetricians and Gynaecologists: Evidence-based Clinical Guideline, No 7, 2011

    "Osmotic dilators are safe and effective for preoperative cervical preparation prior to Dilation&Evacuation procedure (level A)"
    Society of Family Planning: Clinical Guidelines, 2007

    “Of all the available osmotic cervical dilators, DILAPAN-S® achieves the greatest cervical dilation in the shortest timeframe. For same day procedures, DILAPAN-S® is preferable to laminaria.”
    Society of Family Planning: Clinical Guidelines, 2007



    Comparison of efficacy of DILAPAN-S® and laminarias:

    In comparison to natural laminarias, DILAPAN-S® is evaluated as the product with higher efficacy. Homogenous, non-porous synthetic material and certified production process, that includes sterilization by gamma irradiation, minimizes the risk of infectious complications.

    DILAPAN-S®: 98%
    Laminarias, group A: 56%
    Laminarias, group B: 40%

    Recommended size and number of dilators:

    • Preparation of the cervix prior to hysteroscopy or termination of pregnancy / missed abortion under 12 weeks of gestation:
      • Usually 1 piece
      • DILAPAN- S® 3x55mm or 4x55mm
    • Preparation of the cervix prior to the termination of pregnancy in later stage (2nd trimester):
      • Usually, 2-3 pieces are used, however, it is possible to use more dilators if they can be inserted without major resistance (3-5) and leave 12 hours in situ
      • DILAPAN-S® 4x65mm
  • Cervical ripening prior to labor induction

    Dilapan–S® Labor Preinduction
    (click video below for details)

    Gentle and predictable preinduction of labor

    “Preinduction is a set of methods that result in ripening of the cervix in the means of its pliability, shortening and softening”
    Roztočil A.: Preindukce a indukce porodu — Doporučený postup, 2010

    “The maturity of the cervix is an indicator of the likelihood that the labor induction will result in successful vaginal delivery”
    Ramos, L. S. et al.: Induction of Labor, Obstetrics and Gynecology Clinics of North America, 2005

    DILAPAN-S® significantly enhances cervical ripening and increases the Bishop Score enabling effective and safe labor induction.

    Labor induction should be initiated only with sufficiently matured cervix (Bishop Score higher than 5).

    The use of DILAPAN-S® is linked with minimum uterine activity during the ripening process

    “Onset of regular uterine activity as a result of preinduction is a negative and unwanted side effect”
    Roztočil et al.: Kontroverze a chyby v indukci porodu, Moderni gynekologie a porodnictví, 2007

    “The principal role of the agents used for cervical ripening is to soften an unripe cervix independent of uterine activity"
    Ramos, L. S. et al.: Induction of Labor, Obstetrics and Gynecology Clinics of North America, 2005

    Recommended size and number of dilators:

    • With regards to the expected shortening of the cervix it is recommended to use DILAPAN-S® 4x55mm size
    • Usually, 2-3 pieces are used, however, it is possible to use more dilators if they can be inserted without major resistance (3-5) and leave 12 hours in situ